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1.
J Educ Health Promot ; 13: 109, 2024.
Article En | MEDLINE | ID: mdl-38726082

BACKGROUND: The purpose of this study was to investigate the effect of acrylic full removable dentures on the perception of four primary tastes (sweet, sour, salty, and bitter), as well as to determine if there is a correlation between changes in body mass index (BMI) and taste perception. MATERIALS AND METHODS: A total of 60 patients who wore acrylic removable dentures and 60 controls were included in the study as a convenient sample. Sixteen solutions for basic tastes were prepared, and the patients were asked to identify the taste of each solution from the lowest concentration. Anthropometric measures, such as height and weight, were measured and recorded in an MS-Excel sheet. The data were analyzed using SPSS version 23. RESULTS: The results showed that patients with complete removable dentures had lower taste scores for sourness (P < 0.001) and sweetness (P < 0.001) compared to the control group. However, there was no significant difference in salt taste scores (P = 0.218) and bitterness (P = 0.002) between the two groups. Additionally, the study found a correlation between lower BMI values and higher taste scores among denture-wearing patients, indicating an inverse relationship between total taste scores and BMI. CONCLUSIONS: The study suggests that geriatric patients with complete dentures have reduced taste sensations compared to those without dentures which can have a negative impact on their nutritional status. Therefore, it is crucial to provide adequate nutritional support and dietary counseling for geriatric patients based on health policy to maintain their overall health and well-being.

2.
P R Health Sci J ; 42(4): 332-334, 2023 Dec.
Article En | MEDLINE | ID: mdl-38104293

Mucopolysaccharidosis (MPS) is a metabolic disorder resulting from a deficiency of lysosomal enzymes. It is an autosomal recessive disorder with similar incidences in men and women. Mucopolysaccharidosis type IV A is caused by a deficiency of N-acetylgalactosamine-6-sulfatase, which deficiency is, in turn, caused by alterations in the GALNS gene. It is marked by a short stature, a pigeon chest, frontal bossing, kyphosis, and a flat nasal bridge. Intraorally, macroglossia, hypodontia, dentinogenesis imperfecta, a broad mouth, and an anterior open bite are some of the common features. The present paper reports on a case of MPS in a 5-year-old male patient, along with providing a review of the literature and insight into the oral manifestations related to MPS IV A, also called Morquio A syndrome, and its dental treatment. It aims to highlight the clinical recommendations for oral health care in such cases during different phases of MPS IV A treatment.


Chondroitinsulfatases , Mucopolysaccharidosis IV , Male , Humans , Child , Female , Child, Preschool , Mucopolysaccharidosis IV/genetics , Mucopolysaccharidosis IV/therapy , Chondroitinsulfatases/genetics , Chondroitinsulfatases/metabolism , Delivery of Health Care
3.
Oncology (Williston Park) ; 37(11): 449-554, 2023 11 08.
Article En | MEDLINE | ID: mdl-38032303

Gorlin-Goltz syndrome, also known as Gorlin syndrome, basal cell nevus syndrome, and nevoid basal cell carcinoma syndrome, is an autosomal dominant genetic disorder. Its hallmark is an early onset of basal cell carcinoma. Additionally, the syndrome is characterized by a spectrum of distinct clinical attributes encompassing oral, skeletal, ophthalmic, neurological, and developmental aberrations. This condition arises due to anomalies in the Hedgehog signaling pathway, leading to constant pathway activity and uncontrolled growth of tumor cells. Early identification of the disorder through available diagnostic methods and clinical and radiological findings is crucial for accurate diagnosis, which subsequently leads to the formulation of an effective treatment regimen. The purpose of this case report is to discuss the role of a dentist in early detection based on various author-prescribed criteria and the need for a multidisciplinary approach to the treatment of patients with this syndrome.


Basal Cell Nevus Syndrome , Hedgehog Proteins , Humans , Basal Cell Nevus Syndrome/diagnosis , Basal Cell Nevus Syndrome/genetics
4.
J Cancer Res Ther ; 19(Suppl 2): S986-S990, 2023 Jan 01.
Article En | MEDLINE | ID: mdl-38384098

ABSTRACT: Ewing's sarcoma of bone is a rare malignant round cell tumor of the head and neck. The jaw, particularly the mandible, accounts for 3% of occurrences in the head and neck area. These tumors have been reported more frequently in men than in women, and they are usually between 5- and 20-year-old. It is difficult for clinicians and pathologists to make a diagnosis based solely on clinical and microscopic findings. Immunohistochemistry presents a plausible tool that can help the pathologist to arrive at a confirmatory diagnosis. This jaw tumor has the best prognosis when detected and treated early in the disease course, so the importance of timely, and accurate diagnosis cannot be overemphasized. The highlighting feature of this case report of an 18-year-old male that was primary detected by immunohistochemically as Ewing's sarcoma and is localized to the impacted left mandibular molars.


Jaw Neoplasms , Sarcoma, Ewing , Adolescent , Humans , Male , Immunohistochemistry , Mandible/diagnostic imaging , Mandible/pathology , Prognosis , Sarcoma, Ewing/diagnosis , Sarcoma, Ewing/pathology
5.
Vaccines (Basel) ; 10(12)2022 Dec 06.
Article En | MEDLINE | ID: mdl-36560491

Globally, the pandemic of the coronavirus disease, which started in Wuhan, China, has become a major issue for public health. The COVID-19 epidemic notably causes health professionals to experience significantly more emotional stress than the general populace. The present study proposes to investigate the fear aspect in dentists in the initiation of clinical practice during these times. An online cross-sectional study was conducted among dental practitioners based on a pre-validated questionnaire. The data were expressed as frequency and percentage analyzed using the chi-square test using SPSS version 25. The data was obtained from 271 participants, where clinical practice after the first wave was mostly by freelancers (p-value = 0.01); most of whom were married (p-value = 0.065); 19.1% attached to institutes did not have changes in earnings; 28.1% of private practitioners had less than 10% reduction in cases. A total of 62% of private practitioners are concerned about the vaccine's preventative effects (p-value = 0.026), and 57% of private practitioners worry about being sued for the delay in treatment (p-value = 0.036). Only 33.1% of employees in institutions worry that becoming sick could endanger their family. As dentists continue to work their way through this pandemic, these pressures only occasionally have an impact on them. According to the researchers, this is the first study that has captured the anxiety and apprehensions that dental practitioners experienced during the height of the COVID-19 outbreak in India in April 2021. The study's findings demonstrate that the study population was generally upbeat and confident that they could quickly overcome their fear.

6.
J Oral Biol Craniofac Res ; 12(3): 401-404, 2022.
Article En | MEDLINE | ID: mdl-35615340

Objective: Tobacco is the most significant social burden and the leading cause of death. Tobacco is derived from "Nicotiana tabacum" which has nicotine as the main component. There are various disadvantages from tobacco on health which are reported in the medical literature. But the risk of caries among these tobacco users, such as chewers and smokers, is still debatable. Hence, the present study aims to determine the prevalence of dental caries among tobacco chewers and smokers. Materials and methods: In this study, 389 individuals were included. Out of 389 individuals, 304 were men and 85 were women aged between 18 and 60 years. They were classified into two groups. Group A had 207 individuals with habitual tobacco chewing, and Group B had 182 individuals with habitual tobacco smoking and provided a 6 months history. The DMFT index (Decayed, Missing, and filled teeth index-WHO modification 1997) was used to assess caries. Results: The study revealed a higher prevalence of dental caries among tobacco chewers compared to tobacco smokers. The DMFT scores were higher among gutka chewers compared to other types of tobacco use. The lower posterior tooth region showed higher dental caries in tobacco chewers compared to smokers. Conclusion: The higher presence of caries in the tobacco chewing group is due to the presence of sweeteners, which act as cariogenic agents. Similarly, smokers have a thiocyanate component that acts as an anticariogenic agent; therefore, the prevalence of caries was lower in tobacco smokers.

7.
Oral Oncol ; 127: 105768, 2022 04.
Article En | MEDLINE | ID: mdl-35189583

Inverted sinonasal papilloma is an infrequent tumor that mostly affects the elder group of 40-50 yr. This tumor is distinguished from other sinonasal tumors by three characteristics: a high rate of recurrence, carcinomatous changes, and a high potential for local destruction. In 40% of cases of inverted sinonasal papilloma showed an association with the human papillomavirus and considered as the main etiological agent. Here, we present a case of a 36-year-old male presented with pus discharge from the right upper back teeth region in the past 1 year. Correlating with clinical, radiographical features, a diagnosis of the Inverted sinonasal papilloma.


Nose Neoplasms , Papilloma, Inverted , Paranasal Sinus Neoplasms , Adult , Aged , Humans , Male , Neoplasm Recurrence, Local , Nose Neoplasms/diagnostic imaging , Papilloma, Inverted/diagnostic imaging , Papilloma, Inverted/pathology , Papillomaviridae , Paranasal Sinus Neoplasms/pathology
8.
Int J Surg Case Rep ; 92: 106807, 2022 Mar.
Article En | MEDLINE | ID: mdl-35180588

INTRODUCTION AND IMPORTANCE: Rhinosporidiosis is a chronic, localized granulomatous infectious disease caused by Rhinosporidium seeberi that predominantly affects the mucosal membranes of the nose and nasopharynx, conjunctiva, and urethra. Rhinosporidium seeberi is a eukaryotic pathogen that spreads in certain geographical areas, particularly in tropical and subtropical areas, through aquatic exposure. CASE PRESENTATION: We present the case of a young man who had been suffering from a right nasal mass for four months, and whose diagnosis was confirmed after surgical excision and histopathological examination, which revealed distinct pathognomonic findings. Laser-assisted endoscopic excision, in combination with Dapsone, is recommended as a more effective treatment to prevent a recurrence. CLINICAL DISCUSSION: For clinicians, it has been advised to obtain a detailed case history of exposure in patients diagnosed with Rhinosporidiosis. Rhinosporidiosis can be diagnosed with a simple examination of H&E-stained histopathological sections. Because chemotherapy has not been proven to be effective, Laser-assisted endoscopic excision, in combination with Dapsone is the recommended treatment for Rhinosporidiosis. CONCLUSION: One of the differential diagnoses for Rhinosporidiosis in the nasal cavity is masses or abnormal growths without bleeding, which should be kept in mind by clinicians and pathologists.

9.
J Oral Maxillofac Pathol ; 26(4): 576-579, 2022.
Article En | MEDLINE | ID: mdl-37082087

An aneurysmal bone cyst (ABC) is a non-neoplastic, rapidly expanding pathologic bone lesion that mostly affects the mandible and is most commonly found in the first to third decade of life. The most of the ABC cases are locally aggressive osteolytic lesion with a high recurrence rate. As a result, we present a swelling with pus discharge at the maxillary alveolus in a 68-year-old female who was diagnosed with ABC after a computed tomography scan and histological analysis. The conservative surgical excision was performed without considerable bleeding, and no recurrence was observed even after a five-year follow-up period.

10.
J Pharm Bioallied Sci ; 13(Suppl 2): S1244-S1250, 2021 Nov.
Article En | MEDLINE | ID: mdl-35017964

INTRODUCTION: Objective: To assess the antioxidant property of 10% amla extract in reversing the compromised bond strength and to assess the antioxidant property of 10% amla extract and Elsenz on the color stability of power bleached teeth. MATERIALS AND METHODS: Ninty extracted single-rooted maxillary anterior were collected and divided as follows: The labial surfaces of 30 samples were subjected to power bleaching after which the samples were divided into three groups- Group I (control), Group II (antioxidant amla), and Group III (Elsenz) with n = 10 in each which were then stained with a coffee solution for 10 mins. The color difference was recorded with a colorimeter at baseline, after bleaching, after 7, and after 15 days of staining. sixty specimens were randomly divided into six groups (n = 10) as following: Group I (immediate bonding); Group II (bleaching + immediate bonding); Group III (bleaching + antioxidant and immediate bonding); Group IV (bleaching + 1 week storage + antioxidant + bonding); Group V (bleaching + 2 week storage + antioxidant + bonding); Group VI (bleaching + 2 week storage + bonding). All the specimens were tested for shear bond strength in universal testing machine. Statistical analysis was performed using ANOVA and Scheffe's post hoc test. RESULTS: Significantly higher staining was observed in Group II (amla) and least with Elsenz pasteThe highest mean shear bond strength was found in Group I followed by Group V. CONCLUSION: Elsenz showed the least staining followed by artificial saliva. 10% Amla extract neither was effective in preventing staining of power bleached enamel nor in restoring the poor bond strength of power bleached enamel.

11.
J Oral Maxillofac Pathol ; 18(1): 42-5, 2014 Jan.
Article En | MEDLINE | ID: mdl-24959036

AIM OF THE STUDY: To identify and count the number of apoptotic cells in oral lichen planus (OLP) and correlate with the degree of keratinization, thickness of epithelium and thickness of lymphocytic infiltration of OLP. MATERIALS AND METHODS: The study comprised 40 diagnosed cases of OLP. Sections were stained with hematoxylin and eosin to identify and count the number of apoptotic cells. Measurement of other histopathological parameter of OLP such as degree of keratinization, thickness of epithelium and thickness of lymphocytic infiltration was done by using stage micrometer and eyepiece graticule. Statistical analysis was done to understand the correlation between apoptotic cells and histopathological features of OLP. RESULT: The result showed that the number of apoptotic cells increased, with an increase in thickness of lymphocytic infiltration and degree of keratinization, but there was a decrease in the epithelial thickness. CONCLUSION: Further immunological and molecular studies are required for a stronger evidence in correlating apoptotic cell and histological parameters of OLP.

12.
J Oral Maxillofac Pathol ; 17(3): 392-6, 2013 Sep.
Article En | MEDLINE | ID: mdl-24574658

Verruciform xanthoma is a very uncommon papillary growth seen chiefly in the oral mucosa. The presence of foam cells in the connective tissue papillae between the epithelial rete ridges forms the hallmark in its diagnosis. There has been wide speculation and various hypotheses put forth in explaining the etiopathogenesis of verruciform xanthoma and the origin of foam cells. This article aims to update the different hypotheses in understanding the pathogenesis of the lesion.

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